Sleep disturbance and its association with depression and anxiety among Saudi adolescents and young adults: a systematic review
DOI:
https://doi.org/10.65759/bwcrds44Keywords:
Sleep disturbance, sleep quality, insomnia, depression, anxietyAbstract
Background: Sleep disturbance is increasingly reported among adolescents and young adults and is its linked with psychological symptoms. In Saudi Arabia, university and healthcare students represent an important young adult group exposed to academic stress, digital screen use, and irregular sleep habits. Objective: This systematic review aimed to analyze the association between sleep disturbance and depression or anxiety in Saudi adolescents and young adults. Methods: Our systematic review was guided by PRISMA principles. Electronic databases were searched, including PubMed, Web of Science, PubMed Central, MEDLINE, Scopus, and Embase. Eligible studies were original observational studies conducted in Saudi Arabia, included adolescents or young adults, assessed sleep disturbance, poor sleep quality, or insomnia, and reported depression or anxiety outcomes. We exclude reviews, editorials, commentaries, case reports, non-Saudi studies, and studies without relevant sleep or mental health outcomes. Data were extracted on study characteristics, population, sample size, assessment tools, sleep outcomes, depression, anxiety, and reported associations. Results: We include eight original cross-sectional studies. All studies were conducted among Saudi university, medical, or healthcare students, so the data mainly represented young adults rather than school adolescents. Poor sleep quality ranged from 63.2% to 80.3% in PSQI-based studies, while insomnia ranged from 19.3% to 34.9% in ISI-based studies. Depression and anxiety were common in the included studies. Most studies reported significant associations between poor sleep quality or insomnia and higher depression, anxiety, or stress symptoms. Conclusion: Sleep disturbance is common in Saudi young adults and is associated with depression and anxiety.
References
1. Al-Khani AM, Sarhandi MI, Zaghloul MS, Ewid M, Saquib N. A cross-sectional survey on sleep quality, mental health, and academic performance among medical students in Saudi Arabia. BMC Res Notes. 2019 Oct 30;12(1):665. doi: 10.1186/s13104-019-4713-2.
2. Albasheer OB, Al Bahhawi T, Ryani MA, Arishi AM, Hakami OM, Maashi SM, Al-Khairat HK, Alganmy OM, Sahal YA, Sharif AA, Mahfouz MS. Prevalence of insomnia and relationship with depression, anxiety and stress among Jazan University students: A cross-sectional study. Cogent Psychol. 2020;7(1):1789424. doi: 10.1080/23311908.2020.1789424.
3. Alkaabba A, Hussein G, Albader M, Assiri OF, Alosaimi BM, AL Musaad MN, Khamsah MA, Alzahrani BM, Al Sharani AH, Asiri NA, Alotaibi AF, Alshahwan A, Alwalah MA. The digital dilemma: patterns of screen time, sleep quality, and mental health among Saudi university students. Cureus. 2025 Sep 9;17(9):e91882. doi: 10.7759/cureus.91882.
4. Alrashed FA, Sattar K, Ahmad T, Akram A, Karim SI, Alsubiheen AM. Prevalence of insomnia and related psychological factors with coping strategies among medical students in clinical years during the COVID-19 pandemic. Saudi J Biol Sci. 2021 Dec;28(12):6508-6514. doi: 10.1016/j.sjbs.2021.07.012.
5. Alwhaibi M, Al Aloola NA. Associations between stress, anxiety, depression and sleep quality among healthcare students. J Clin Med. 2023 Jun 28;12(13):4340. doi: 10.3390/jcm12134340.
6. Chai R, Bian WJ. Adolescent sleep and its disruption in depression and anxiety. Front Neurosci. 2024 Nov 7;18:1479420. doi: 10.3389/fnins.2024.1479420.
7. Gosadi IM, Shnaimer JA. Association between depression, anxiety, and stress and sleep quality among university students from Saudi Arabia: a cross-sectional study. Psychol Res Behav Manag. 2025;18:2287-2298. doi: 10.2147/PRBM.S562798.
8. Ibrahim NK, Badawi FA, Mansouri YM, Ainousa AM, Jambi SK, Fatani AN, Andijani RA. Sleep quality among medical students at King Abdulaziz University: a cross-sectional study. J Community Med Health Educ. 2017 Oct 16;7(5):561. doi: 10.4172/2161-0711.1000561.
9. Marino C, Andrade B, Campisi SC, Wong M, Zhao H, Jing X, Aitken M, Bonato S, Haltigan J, Wang W, Szatmari P. Association between disturbed sleep and depression in children and youths: a systematic review and meta-analysis of cohort studies. JAMA Netw Open. 2021 Mar 1;4(3):e212373. doi: 10.1001/jamanetworkopen.2021.2373.
10. Yaghmour KA, Alhmyri SM, Alhmyri BM, Sharaf R, Alasmari MA, Almilabi MM. The effect of sleep quality and mental health on academic performance among the medical students of King Abdulaziz University. Cureus. 2023 Sep 9;15(9):e44951. doi: 10.7759/cureus.44951.
11. Ahmed I, Hazell CM, Edwards B, Glazebrook C, Davies EB. A systematic review and meta-analysis of studies exploring prevalence of non-specific anxiety in undergraduate university students. BMC Psychiatry. 2023 Apr 11;23(1):240. doi: 10.1186/s12888-023-04645-8.
12. Carter B, Rees P, Hale L, Bhattacharjee D, Paradkar MS. Association between portable screen-based media device access or use and sleep outcomes: a systematic review and meta-analysis. JAMA Pediatr. 2016 Dec 1;170(12):1202-1208. doi: 10.1001/jamapediatrics.2016.2341.
13. Chan MF, Al Balushi R, Al Falahi M, Mahadevan S, Al Saadoon M, Al-Adawi S. Child and adolescent mental health disorders in the GCC: A systematic review and meta-analysis. Int J Pediatr Adolesc Med. 2021 Sep;8(3):134-145. doi: 10.1016/j.ijpam.2021.04.002.
14. Dinis J, Bragança M. Quality of sleep and depression in college students: a systematic review. Sleep Sci. 2018 Nov-Dec;11(4):290-301. doi: 10.5935/1984-0063.20180045.
15. Gardani M, Bradford DR, Russell K, Allan S, Beattie L, Ellis JG, Akram U. A systematic review and meta-analysis of poor sleep, insomnia symptoms and stress in undergraduate students. Sleep Med Rev. 2022 Feb;61:101565. doi: 10.1016/j.smrv.2021.101565.
16. Ibrahim AK, Kelly SJ, Adams CE, Glazebrook C. A systematic review of studies of depression prevalence in university students. J Psychiatr Res. 2013 Mar;47(3):391-400. doi: 10.1016/j.jpsychires.2012.11.015.
17. Li W, Zhao Z, Chen D, Peng Y, Lu Z. Prevalence and associated factors of depression and anxiety symptoms among college students: a systematic review and meta-analysis. J Child Psychol Psychiatry. 2022 Nov;63(11):1222-1230. doi: 10.1111/jcpp.13606.
18. Silva SS, Silveira MAC, Almeida HCR, Nascimento MCP, Santos MAM, Heimer MV. Use of digital screens by adolescents and association on sleep quality: a systematic review. Cad Saude Publica. 2022 Oct 24;38(10):e00300721. doi: 10.1590/0102-311XEN300721.
19. Tadros M, Newby JM, Li S, Werner-Seidler A. A systematic review and meta-analysis of psychological treatments to improve sleep quality in university students. PLoS One. 2025 Feb 13;20(2):e0317125. doi: 10.1371/journal.pone.0317125.
20. Wang F, Bíró É. Determinants of sleep quality in college students: A literature review. Explore (NY). 2021 Mar-Apr;17(2):170-177. doi: 10.1016/j.explore.2020.11.003.


